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T*
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T*
[(or)-186.5(ingested)-189.8(orally.)-190(Images)-194.3(are)-189.9(then)-184.2(obtained)-189.9(to)-186.6(document)-191.1(sites)]TJ
0 -1.1174 TD
[(of)-278.6(accumulat)-10.3(ion)-279.9(within)-278.6(the)-281.1(body.)]TJ
1.0137 -1.1116 TD
[(W)13.9(h)0(e)19.7(n)-173.9(ad)19.7(v)16.2(i)0(s)20.9(i)0(n)26.5(g)-179.6(th)26.5(e)-180.8(b)16.2(re)19.7(as)25.6(tf)20.7(ee)24.3(di)20.7(ng)-163.5(pa)19.7(t)16.1(i)0(e)19.6(n)16.2(t,)-165.9(co)19.7(n)16.2(s)0(i)20.9(d)0(e)25.4(r)0(a)19.7(t)0(i)26.3(o)0(n)-169.2(m)15(us)21(t)]TJ
-1.0137 -1.1116 TD
[(be)-302.9(g)16.2(i)0(v)20.7(e)0(n)-302.9(t)16.1(o)-312.1(t)0(h)20.7(e)-313.3(fa)25.5(ct)-303(th)26.5(at)-303(a)-313.3(c)0(h)25.4(i)0(l)20.6(d)-312.1(m)15(a)0(y)-302.9(b)0(e)-302.9(e)15(xp)20.8(os)26.8(ed)-302.9(to)-301.8(ra)25.5(di)20.7(a)15(t)0(i)20.6(o)0(n)]TJ
0 -1.1174 TD
[(th)20.7(r)16.2(o)0(u)20.8(g)0(h)-347.8(t)16.1(wo)-348.7(ro)20.9(u)16.2(t)0(e)19.5(s)0(.)-344.2(T)0(h)19.6(e)-353.6(mo)19.6(st)-347.7(c)15(o)0(m)19.6(m)15(on)-347.8(ro)26.6(ut)20.7(e)-359.4(o)0(f)-347.8(e)15(xp)20.8(os)26.8(ur)20.9(e)-359.4(i)0(s)]TJ
0 -1.1116 TD
[(ra)19.7(d)16.2(i)0(o)20.7(a)0(c)24.3(t)0(i)20.6(v)0(i)26.5(t)0(y)-192.4(w)0(i)19.8(t)0(h)26.5(i)0(n)-192.4(t)0(h)20.7(e)-203.8(in)20.7(g)16.2(e)0(s)19.9(t)0(e)25.3(d)-208.4(m)15(i)0(l)20.6(k)-202.7(it)20.6(s)16.4(e)0(l)19.5(f)0(.)-188.8(T)0(h)19.6(e)-203.8(ot)20.7(h)16.2(e)0(r)-193.4(p)0(o)20.8(s)0(s)21.2(i)16.1(bl)20.7(e)]TJ
T*
[(ro)20.9(u)16.2(t)0(e)-199.3(t)0(o)-192.4(c)0(o)19.7(n)16.2(si)20.9(de)25.4(r)-208.4(i)0(s)-198(e)15(xt)20.7(er)25.5(na)19.7(l)-202.8(e)0(x)19.7(p)0(o)26.6(s)0(u)21(r)0(e)-193.4(w)0(h)20(i)0(l)26.3(e)-209.6(in)-192.4(pr)20.9(ox)26.6(im)19.5(it)26.3(y)-208.4(t)0(o)-192.4(t)0(h)20.7(e)]TJ
0 -1.1174 TD
[(mo)25.4(th)20.7(er)25.5(.)-320.2(T)15(hi)20.7(s)-317.7(s)16.4(ec)18.5(on)26.6(d)-317.9(s)0(i)20.9(t)16.1(ua)19.7(ti)26.3(on)-307.5(o)16.2(c)0(c)18.5(u)0(r)26.6(s)-317.7(wh)20(e)15(n)-317.9(me)24.2(ta)19.6(b)16.2(o)0(l)20.7(i)0(c)25.3(a)0(l)19.5(l)0(y)-301.8(a)0(c)18.5(-)]TJ
0 -1.1116 TD
[(ti)20.6(v)16.2(e)-382.4(l)16.1(a)0(c)18.5(t)0(a)25.3(t)0(i)20.6(n)0(g)-365.1(b)0(r)26.6(e)0(a)18.5(s)0(t)-365(t)0(i)20.6(s)16.4(su)21(e)-376.6(c)0(o)19.7(n)0(c)25.4(e)0(n)19.7(t)16.1(ra)19.7(te)25.3(s)-381(t)0(h)26.5(e)-382.4(a)15(d)0(m)19.6(i)0(n)26.5(i)0(s)20.9(t)0(e)25.3(r)0(e)19.7(d)-375.5(ra)19.7(-)]TJ
T*
[(di)20.7(o)16.2(a)0(c)18.5(t)0(i)26.3(v)0(i)20.7(t)0(y)26.5(.)-343.3(Th)19.6(i)16.1(s)-346.5(s)16.4(e)0(c)18.5(o)0(n)26.6(d)-346.7(r)16.2(o)0(u)20.8(t)0(e)-331.8(o)0(f)-330.5(e)0(x)25.4(p)0(o)20.8(s)0(u)26.8(r)0(e)-337.4(i)16.1(s)-346.5(o)16.2(nl)20.7(y)-340.9(a)-342.1(co)19.7(nc)25.4(er)19.7(n)]TJ
T*
[(wi)19.8(t)16.1(h)-283.3(u)21(de)25.4(ox)20.8(y)16.2(g)0(l)20.7(u)0(c)25.4(o)0(s)21(e)0(-)19.7(F)16.3(18)-272.9(\(F)21(D)15.3(G)0(\))20(,)-279.9(th)20.7(e)-284.5(a)15(ge)19.7(nt)-273(u)16.2(s)0(e)19.9(d)-283.3(fo)26.6(r)-283.3(p)0(o)20.8(s)0(i)26.7(t)0(r)20.7(o)0(n)]TJ
0 -1.1174 TD
[(em)24.2(is)20.9(si)20.9(o)16.2(n)-173.9(to)20.7(mo)25.4(gr)20.9(ap)25.4(hy)-163.5(\(P)21(E)15(T)0(\))19.7(.)-176.2(T)15(h)0(e)-164.6(o)0(t)20.7(h)16.2(er)-164.6(ag)19.7(e)15(n)0(t)20.7(s)-173.7(di)20.7(s)16.4(c)0(u)19.7(s)0(s)21.2(e)15(d)-173.9(d)0(o)-163.5(n)0(o)20.8(t)]TJ
0 -1.1116 TD
[(ac)24.3(cu)19.7(mu)25.4(la)19.6(t)16.1(e)-382.4(w)15.3(i)0(t)20.6(h)0(i)26.5(n)-381.2(a)15(c)0(t)19.5(i)0(v)26.5(e)-382.4(b)16.2(r)0(e)19.7(a)0(s)25.6(t)-381.4(t)16.1(i)0(s)20.9(s)0(u)21(e)15(.)]TJ
7.3823 0 0 6.5614 215.7732 415.3322 Tm
-.0162 Tc
(22)Tj
9.843 0 0 9.843 226.7149 410.9668 Tm
0 Tc
[(Th)19.6(e)-376.6(r)0(i)20.7(s)16.4(ks)-370.6(i)16.1(n)0(v)20.8(o)0(l)26.5(v)0(e)19.7(d)]TJ
-16.7319 -1.1116 TD
[(wi)19.8(t)16.1(h)-260.3(sp)21(e)15(c)0(i)19.5()16.3(c)-261.4(a)0(g)19.7(e)15(nt)20.7(s)-254.3(a)0(r)19.7(e)-261.4(d)16.2(i)0(s)20.9(c)0(u)25.4(s)0(s)21.2(e)0(d)-245.3(h)0(e)19.7(r)0(e)25.5(u)0(n)20.8(d)16.2(er)19.7(.)]TJ
1.0137 -1.1174 TD
[(Es)19.8(ti)20.6(m)15(a)0(t)19.5(e)0(d)-268.3(r)0(a)19.7(d)0(i)20.7(a)15(ti)20.6(on)-267.1(do)20.8(se)19.9(s)-277.4(t)0(o)-267.3(t)0(h)20.7(e)-273(ch)19.7(il)20.6(d)-277.6(f)0(r)20.9(o)0(m)-268.4(i)0(n)20.7(g)16.2(es)19.9(te)19.6(d)-277.6(r)0(a)19.7(d)0(i)20.7(o)0(-)]TJ
-1.0137 -1.1116 TD
[(ac)18.5(ti)20.6(vi)20.7(ty)-307.6(ha)25.4(ve)-314.4(b)16.2(e)0(e)18.5(n)-317.9(re)19.7(po)20.8(rt)20.7(ed)-308.6(fo)20.9(r)-317.8(t)0(h)20.7(e)-319(mo)19.6(st)-307.4(co)19.7(mm)24.1(on)-307.5(ra)19.7(di)20.7(op)20.8(ha)19.7(r-)]TJ
T*
[(ma)18.4(ce)24.3(ut)20.7(ic)19.5(al)19.5(s)-237(u)16.2(se)19.9(d)-237.2(i)0(n)-221.2(d)0(i)20.7(a)0(g)19.7(n)0(o)20.8(s)0(t)20.9(i)0(c)-222.4(n)0(u)20.8(c)0(l)19.5(e)0(a)18.5(r)-231.5(me)18.4(di)20.7(ci)25.3(ne)19.7(.)-233.8(A)0(s)-227.5(a)-232.6(ge)19.7(ne)19.7(ra)19.7(l)]TJ
0 -1.1174 TD
[(ru)20.9(le)19.5(,)-279.9(n)0(o)-272.9(i)0(n)20.7(t)0(e)19.6(r)0(r)20.9(u)0(p)20.8(t)0(i)26.3(o)0(n)-272.9(o)0(f)-272.9(b)0(r)20.9(e)0(a)18.5(s)0(t)20.9(f)0(e)19.7(e)0(d)25.4(i)0(n)20.7(g)-283.3(is)-272.8(re)19.7(qu)20.8(ir)20.7(ed)-274.1(fo)26.6(r)-283.3(r)0(a)19.7(d)0(i)20.7(a)0(t)19.5(i)0(o)20.7(n)]TJ
0 -1.1116 TD
[(do)20.8(se)19.9(s)]TJ
/F10 1 Tf
2.5573 0 TD
(<)Tj
/F6 1 Tf
.5414 0 TD
[(10)20.8(0)-381.2(m)15(re)19.7(m)-382.5(\()0(1)-370.8(m)0(S)19.8(V)0(\))20(.)]TJ
7.3823 0 0 6.5614 174.5574 349.5684 Tm
-.0162 Tc
(23)Tj
9.843 0 0 9.843 185.6125 345.2031 Tm
0 Tc
[(Bo)19.8(t)16.1(h)-381.2(th)20.7(e)-382.4(N)0(u)20(c)0(l)19.5(e)0(a)18.5(r)-381.2(R)15.2(e)0(g)19.7(u)0(l)20.7(a)0(t)19.5(o)0(r)20.9(y)]TJ
-12.5562 -1.1116 TD
[(Co)19.8(mm)24.1(is)20.9(si)20.9(on)-336.3(\(N)20(RC)18.8(\))-346.6(a)0(n)19.7(d)-346.7(In)20.9(te)19.6(rn)26.6(at)19.5(io)20.7(na)19.7(l)-346.8(C)0(o)19.8(m)0(m)24.1(i)0(s)20.9(s)0(i)20.9(o)0(n)-336.3(o)0(n)-336.3(R)0(a)18.6(d)0(i)20.7(-)]TJ
0 -1.1174 TD
[(ol)20.7(og)20.8(ic)19.5(a)15(l)-318(Pr)21(ot)20.7(ec)18.5(ti)20.6(on)-307.5(\(I)26.7(CR)18.8(P\))-307.3(ha)19.7(ve)-308.6(pu)26.6(bl)20.7(is)20.9(he)19.7(d)-317.9(g)0(u)20.8(i)0(d)20.7(e)0(l)25.3(i)0(n)20.7(e)0(s)-308.4(f)0(o)20.9(r)-317.8(th)20.7(e)]TJ
0 -1.1116 TD
[(mo)19.6(st)-532(co)25.4(mm)18.4(on)20.8(ly)-532.2(u)16.2(s)0(e)19.9(d)-542.5(ra)19.7(di)20.7(op)20.8(ha)19.7(r)16.2(m)0(a)18.4(c)0(e)18.5(u)0(t)20.7(i)0(c)19.6(a)15(ls)20.9(.)-544.8(N)0(o)20(t)0(e)-527.6(t)0(h)20.7(a)0(t)-533.4(r)0(e)19.7(-)]TJ
T*
[(co)19.7(mm)24.1(en)19.7(da)19.7(ti)20.6(on)20.8(s)-277.4(f)0(o)20.9(r)-277.5(so)21(m)15(e)-278.7(ag)19.7(en)19.7(ts)-267.1(di)20.7(ff)26.7(er)-268.3(be)19.7(tw)19.8(ee)18.5(n)-277.6(t)0(h)26.5(e)-278.7(NR)18.9(C)-278.6(a)0(n)19.7(d)]TJ
T*
[(IC)19.8(RP)20(,)-337.5(a)0(n)19.7(d)-335.2(th)20.7(e)-342.1(I)0(n)20.9(t)0(e)19.5(r)0(n)20.9(a)15(ti)20.6(on)20.8(al)-331.8(At)19.8(o)16.2(m)0(i)19.5(c)-342.1(En)19.6(e)15(r)0(g)20.9(y)-340.9(Ag)20(en)19.7(c)15(y)-340.9(\(I)20.9(AE)18.8(A\))]TJ
0 -1.1174 TD
[(re)19.7(co)19.7(m)15(m)0(e)18.4(n)0(d)20.8(s)-231.3(an)-216.5(in)20.7(te)19.6(rr)20.9(up)20.8(ti)26.3(on)-221.1(of)-221(br)20.9(e)15(a)0(s)19.9(t)0(f)20.7(e)0(e)18.5(d)0(i)20.7(n)0(g)-215.3(f)0(o)20.9(r)-231.5(fo)20.9(ur)-215.3(ho)20.8(ur)20.9(s)-231.3(o)0(r)]TJ
0 -1.1116 TD
[(on)20.8(e)-434.2(f)0(e)19.7(e)0(d)19.7(i)0(n)20.7(g)-433.1(to)-422.8(ac)18.5(co)19.7(un)20.8(t)-433.2(f)0(o)20.9(r)-433(an)19.7(y)-433.1(e)0(x)19.7(t)0(e)19.6(r)0(n)20.9(a)0(l)-424(r)0(a)19.7(d)0(i)20.7(a)0(t)19.5(i)0(o)20.7(n)-433.1(an)19.7(d)-433.1(f)0(r)20.9(e)0(e)]TJ
T*
[(Tc)18.5(99)20.8(m)-267.3(p)0(e)19.7(r)0(t)20.7(e)0(c)24.3(h)0(n)20.8(e)0(t)19.5(a)0(t)19.5(e)-267.2(in)-261.5(th)20.7(e)-267.2(p)0(r)20.9(o)0(d)20.8(u)0(c)19.7(t)0(.)]TJ
7.3823 0 0 6.5614 202.9039 261.9211 Tm
-.0162 Tc
[(22)-16.2()8.5(3)-16.2(1)]TJ
/F2 1 Tf
8.9663 0 0 8.9663 72 233.7448 Tm
0 Tc
[(Positron)-399(emission)-393.6(tomography.)]TJ
/F6 1 Tf
9.843 0 0 9.843 206.7023 233.7448 Tm
[(PET)-339.6(is)-336.2(one)-338.5(of)-336.2(the)-338.7(most)]TJ
-14.6988 -1.1116 TD
[(commonly)-191.1(ordered)-188.5(nuclear)-189.8(medicine)-192.3(studies)-193.1(and)-183(is)-192.2(often)-185.3(used)]TJ
T*
[(in)-209.7(cancer)-207.1(diagnosis)-212.5(and)-206.1(staging.)-208.2(FDG)-212.2(is)-203.7(chemically)-213.1(similar)-211.8(to)]TJ
0 -1.1174 TD
[(glucose,)-209.2(but)-210.8(with)-207.1(the)-211.9(positron-emitting)-211.7(radionuclide)-212.9(uorine-)]TJ
0 -1.1116 TD
[(18)-486(substituted)-485.7(on)-480.3(the)-488.4(molecule)-486.1(allowing)-483.5(identication)-490.6(of)]TJ
T*
[(metabolically)-285.8(active)-286.8(lesions)-279.4(in)-278.8(the)-286.8(body.)]TJ
1.0137 -1.1116 TD
[(FDG)-241(is)-244(not)-245.3(excreted)-243.9(into)-246.6(breast)-245(milk.)-245.5(Contact)-241.7(between)-248.4(the)]TJ
-1.0137 -1.1174 TD
[(mother)-354.7(and)-355.8(child,)-355.9(however,)-359.9(should)-352.1(be)-354.7(limited)-356.2(for)-354.6(12)-353.5(hours)]TJ
0 -1.1116 TD
[(after)-307.4(the)-304.1(injection)-306.5(of)-301.7(FDG)-304.4(due)-304(to)-307.6(radioactivity)-306.4(concentrated)]TJ
T*
[(within)-434.1(the)-430.8(breast)-435.1(tissue)-428.1(itself.)-437.6(Milk)-431.8(can)-431.8(be)-429.6(expressed)-433.4(and)]TJ
0 -1.1174 TD
[(safely)-279.5(given)-271.7(to)-278.8(the)-275.3(child)-277.6(during)-271.7(this)-275.2(time.)-275.4(The)-276.4(milk)-276.6(does)-276.1(not)]TJ
0 -1.1116 TD
[(need)-283.2(to)-278.8(be)-279.8(discarded.)]TJ
/F2 1 Tf
8.9663 0 0 8.9663 72 89.4614 Tm
[(Bone)-548.6(scan.)]TJ
/F6 1 Tf
9.843 0 0 9.843 129.0897 89.4614 Tm
-.0172 Tc
[(Bon)4.7(e)-474.5(scans)-473.1(c)3.6(an)-473.3(be)-468.7(used)-473.3(to)-473.3(detect)-473.4(o)4.7(sseous)]TJ
-6.8137 -1.1174 TD
-.0158 Tc
[(me)5(ta)5(sta)5(t).3(i)6(c)-369.4(dis)6.3(e)-.8(a)5(s).6(e)-369.4(a)-.8(n)6.1(d)-368.2(mo)6.1(st)-368.4(c)5(o).4(m)4.9(m)-.8(on)6.1(ly)-368.2(u)6.1(s).6(e)-369.4(t)6(ech)6.1(ne)5(tiu)6.1(m)-369.5(9).4(9)6.1(m)-.8(-)]TJ
0 -1.1116 TD
-.0171 Tc
[(medr)4.9(onate)-180.6(\()4.9(T)-2.1(c-99)4.8(m)-180.7(M)-1.8(DP\).)-176(Very)-179.5(li)]TJ
13.2761 0 TD
-.0168 Tc
[(tt)5(le)-180.3(Tc-9)5.1(9m)-180.4(MDP)-179(i)-.7(s)-179(e)4(xcret)5(e)-1.8(d)]TJ
-13.2761 -1.1116 TD
[(in)5.2(to)-277(br)5.3(eas)5.4(t)-282.9(m)4(il)5.1(k.)-279.3(No)-282.7(i)5.1(n)-.5(t)5.1(e)-1.7(rr)5.3(upt)5.1(io)5.2(n)-282.7(i)5.1(n)-277(breast)5.1(f)-.5(eedi)5.1(ng)-277(is)-276.8(requi)5.1(red.)]TJ
/F2 1 Tf
8.9663 0 0 8.9663 323.0361 725.7825 Tm
0 Tc
[(Thyroid)-428.5(imaging.)]TJ
/F6 1 Tf
9.843 0 0 9.843 400.3085 725.7825 Tm
[(There)-371.9(are)-362.7(three)-370.8(radionuclides)-369.3(used)-362.5(in)]TJ
-8.8642 -1.1116 TD
[(nucle)-8(ar)-279.8(thyroid)-290.2(imaging:)-282.3(1-131,)-285.4(I-123,)-285.3(and)-286.7(pertechnetate)-286.6(Tc)]TJ
0 -1.1174 TD
[(99m.)-486(I-131)-477.7(is)-480.2(most)-483.6(commonly)-479.1(used)-483.4(for)-481.3(the)-482.6(treatment)-481.5(of)]TJ
0 -1.1116 TD
[(thyroi)-6.8(d)-289.1(cancer)-293.5(or)-290.1(Graves)-292.9(disease.)-296.6(Although)-292.2(it)-290.4(is)-290.1(sometimes)]TJ
T*
[(used)-408.6(to)-405.5(assess)-411.3(metastases)-414(in)-405.5(the)-407.8(setting)-406.5(of)-405.3(thyroid)-411.1(cancer,)]TJ
0 -1.1174 TD
[(I-131)-218.6(is)-221(generally)-221(not)-216.5(used)-218.5(for)-222.1(routine)-216.4(thyroid)-221.1(imaging)-217.7(due)-217.6(to)]TJ
0 -1.1116 TD
[(its)-297.1(high)-298.3(principle)-300.6(gamma)-298.3(energy)-296.9(\(364)-165.6(keV\),)-297.8(high)-292.5(beta)-300.6(emis-)]TJ
T*
[(sion)-223.2(\(resulting)-225.4(in)-215.4(large)-226.8(dose)-218.5(to)-221.2(the)-217.7(thyroid\),)-225.6(and)-217.6(long)-217.6(half-l)-8(ife)]TJ
0 -1.1174 TD
[(\(8.04)-480.1(days\).)-476.4(Use)-477.4(of)-480.2(I-131)-477.7(requires)-477.5(complete)-480.3(cessation)-479.8(of)]TJ
0 -1.1116 TD
[(breast)-8.8(feeding)-182.9(this)-188.8(child.)-183.2(It)-186.6(is)-180.7(recommended)-192(that)-184.4(breastfeeding)]TJ
T*
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T*
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(32)Tj
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T*
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T*
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T*
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T*
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T*
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T*
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T*
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[(60)-359.3(ho)20.8(ur)20.9(s,)-355.7(ha)19.7(ve)-360.5(el)19.5(ap)19.7(se)14.1(d.)]TJ
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T*
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[(Ventilation-perfusion)-240.4(scan.)]TJ
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[(A)-186.3(ventilation-perfusion)-199.9(\(VQ\))]TJ
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T*
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T*
[(e)-6.4(m)-.7(bo)-5.2(lis)-5(m.)-353.1(The)-352(p).5(e)-6.4(r).6(f)-5.2(u).5(si)-5.3(on)-350.8(ag)-5.2(ent)-350.9(u)-5.2(se)-6.4(d)-350.8(i).4(s)-350.6(t).4(e)-6.4(c)-.6(hn)-5.2(eti)-5.3(u).5(m-)-5.2(99m)-352(ma)-6.4(c-)]TJ
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1.0137 -1.1116 TD
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[(For)-273.8(Tc-99m)-275.1(MAA,)-274.3(12-hour)-272.6(interruption)-274(is)-272.8(recommended.)]TJ
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[(Although)-188.5(no)-192.3(interruption)-187.6(is)-186.4(required)-189.8(for)-193.3(the)-183.1(ventilation)-193.6(agents)]TJ
0 -1.1116 TD
[(Tc-99m)-396.1(DTPA)-393.1(or)-388.1(xenon)-392.6(gas,)-387.8(a)-393.9(12-hour)-387.8(interruption)-395(is)-388(re-)]TJ
T*
[(commended)-205.9(for)-199.1(all)-200.6(VQ)-199.8(scans)-203.3(because)-202.2(these)-203.6(agents)-198.9(are)-201.4(always)]TJ
T*
[(used)-690.8(in)-682(conjunction)-688.7(with)-685.2(the)-684.2(perfusion)-684.8(agent)-687.6(Tc-99m)]TJ
0 -1.1174 TD
(MAA.)Tj
7.3823 0 0 6.5614 85.096 340.9511 Tm
[(34,36)-7.8(,37)]TJ
9.843 0 0 9.843 115.8803 336.5858 Tm
[(During)-491.4(interruption,)-502.1(patients)-495.1(should)-496.1(express)]TJ
-5.7021 -1.1116 TD
[(breast)-515.7(milk)-507(every)-514.7(34)-510.2(hours)-506.4(for)-510.1(1015)-512.4(minutes)-511.3(or)-509(until)]TJ
T*
[(minimal)-386.1(milk)-380.3(ows.)-382.7(The)-380(milk)-386(expressed)-381.6(can)-385.8(be)-377.7(stored)-382.1(re-)]TJ
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[(frigerated)-245.1(and)-234.9(given)-237.2(to)-238.5(the)-235(infant)-238.4(after)-238.3(10)-238.3(physical)-235.8(half-lives,)]TJ
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(or)Tj
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(*)Tj
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[(60)-284.4(hours,)-279.4(have)-283.2(elapsed.)]TJ
7.3823 0 0 6.5614 173.7637 297.1274 Tm
(34,3840)Tj
9.843 0 0 9.843 69.7323 281.8204 Tm
[(It)-382.4(should)-386.7(be)-383.5(noted)-381.2(that)-386(CT)-384.6(angiography)-383.2(is)-388(the)-379(preferred)]TJ
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T*
[(co)13.9(nt)20.7(ra)19.7(st)20.9(.)-199.3(I)0(n)-186.5(t)0(h)20.7(e)-198.1(se)19.9(tt)20.6(in)15(g)-191.2(o)0(f)-192.2(c)0(o)19.7(n)0(t)20.7(r)0(a)19.7(s)0(t)-186.4(a)0(l)19.5(l)0(e)19.6(r)0(g)15.1(y)-196.9(or)-186.5(re)19.7(na)19.7(l)-197.1(i)0(n)20.7(s)0(u)21(f)0()15.3(c)0(i)19.5(e)0(n)19.7(c)0(y)]TJ
T*
[(\(G)14.2(FR)]TJ
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(<)Tj
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[(30)20.8(\),)-223.4(VQ)-222.8(sc)19.9(an)-222.2(ca)18.5(n)-231.5(b)0(e)-222.2(p)0(e)19.7(r)0(f)15.1(o)0(r)20.9(m)0(e)18.4(d)-231.5(wi)19.8(th)-221.2(th)20.7(e)-232.6(a)0(l)19.5(r)0(e)14(a)0(d)19.7(y)-231.5(no)20.8(te)19.5(d)]TJ
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8.9663 0 0 8.9663 59.7543 203.0739 Tm
[(Recommendations)-337.4(for)-337.3(Future)-334(Research)]TJ
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[(The)-334(safety)-337.1(of)-330.5(intravenous)-337(contrast)-339.5(agents)-331.4(and)-338.5(commonly)]TJ
-1.0137 -1.1116 TD
[(used)-270.3(radionuclides)-265.6(has)-269.2(been)-265.9(well)-265.9(studied.)-271.6(As)-262.1(new)-270.3(agents)-262.3(are)]TJ
T*
[(introduced,)-287.7(further)-279.6(research)-283.9(will)-282.1(need)-283.2(to)-278.8(be)-285.6(performed.)]TJ
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[(Annotated)-335.7(Bibliography)]TJ
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[(For)-498.4(more)-502.1(information)-504.4(on)-497.5(radiology)-500.9(and)-505.6(nuclear)-500.9(medi-)]TJ
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[(cine)-865.1(protocols)-863.5(for)-861.4(lactating)-866.4(women,)-864.6(please)-862.5(see)-863.6(the)]TJ
T*
[(Supplementary)-289.8(Data.)]TJ
/F4 1 Tf
8.9663 0 0 8.9663 59.7543 77.5558 Tm
[(Supplementary)-341.9(Material)]TJ
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9.843 0 0 9.843 69.7323 61.1149 Tm
[(Supplementary)-284.1(Data)]TJ
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8.9663 0 0 8.9663 310.8472 725.7825 Tm
(References)Tj
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9.2951 0 0 9.2951 315.496 709.7384 Tm
[(1.)-500.4(Boivin)-401(G,)-404.3(de)-407(Korvin)-400.6(B,)-407.5(Marion)-402.5(J,)-401.9(et)-406.5(al.)-406.5(Is)-404.3(a)-400.8(breast)-406.6(MRI)]TJ
1.2503 -1.1284 TD
[(possible)-289.1(and)-285.2(indicated)-292.8(in)-286.4(case)-286.8(of)-289.3(suspicion)-289.3(of)-283.2(breast)-290.7(cancer)]TJ
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[(Diagn)-331.1(Interv)-339.5(Imaging)]TJ
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(2012;93:823827.)Tj
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[(2.)-500.4(Espinosa)-322.1(LA,)-327.1(Daniel)-326.9(BL,)-324.2(Vidarsson)-324.2(L,)-325.4(et)-327.2(al.)-321.2(The)-329.8(lactating)]TJ
1.2503 -1.1284 TD
[(breast:)-497.7(Contrast-enhanced)-500.5(MR)-498.4(imaging)-497.7(of)-496.6(normal)-494.3(tissue)]TJ
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(Radiology)Tj
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[(3.)-500.4(Expert)-393(Panel)-401.8(on)-390.6(Breast)-399.2(Imaging,)-397(diFlorio-Alexander)-402.5(RM,)]TJ
1.2503 -1.1223 TD
[(Slanetz)-338.6(PJ,)-331.7(et)-339.4(al.)-333.3(ACR)-340.9(appropriateness)-337.9(criteria:)-339.5(Breast)-338.2(im-)]TJ
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[(aging)-345.9(of)-344.2(pregnant)-346.8(and)-346.2(lactating)-347.1(women.)]TJ
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16.7485 0 TD
[(J)-345.9(A)0(m)-345.3(Coll)-345.8(Radiol)]TJ
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(2018;15\(11S\):S263S275.)Tj
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[(4.)-500.4(Helewa)-272.2(M,)-273.9(Levesque)-277.1(P,)-271.5(Provencher)-277.8(D,)-276.3(et)-272.3(al.)-272.4(Breast)-277.2(cancer,)]TJ
1.2503 -1.1223 TD
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[(pregnancy,)-498.6(and)-498.7(b)1.5(reastfeedin)-4.6(g.)]TJ
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[(J)-493.1(O)3.6(bs)6.1(te)7.1(t)-494.4(G)3.6(yn)5.2(ae)7.1(co)5.2(l)-494.4(C).4(a)5.2(n)]TJ
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[(2002)-6.1(;24)-6.1(:).5(164)-6.1(180)-6.1(;)-334.9(qui)-5.6(z)-333.6(181)-6.1(184)-6.1(.)]TJ
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[(5.)-500.4(National)-716.9(Comprehensive)-721.1(Cancer)-715.9(Network)-723.7(Inc.)-714.5(NCCN)]TJ
1.2503 -1.1284 TD
[(Clinical)-463.4(Practice)-473.4(Guidelines)-466.3(in)-463.2(Oncology:)-469.5(Breast)-466.3(Cancer)]TJ
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[(Screening)-317.4(and)-321.8(Diagnosis.)-321.4(2018;)-317.3(Version)-324.8(3.2018.)-318(Available)]TJ
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[(at)-480.1(ht)-4.4(tp)-4.9(s:)-4.4(/)-4.4(/)1.7(ww)-6.5(w)-12.6(.)-4.9(nccn)-17.1(.o)-4.9(rg/)-4.4(p)1.2(r)-7.3(o)1.2(fes)-4(s)2(i)-4.4(o)1.2(n)-4.9(a)-3(ls)-4.1(/p)-4.9(hy)-4.9(si)-4.4(cian)-4.9(_gl)-4.4(s)-4.1(/)1.7(p)-4.9(d)1.2(f/)]TJ
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[(breast-screening)-15.3(.)3(pdf)-334.8(\().6(accessed)-332.5(N)1.4(ovember)-334.8(1)3(,)-332.4(2)-3.1(018\).)]TJ
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[(6.)-500.4(Newman)-390.2(J.)-383.6(Breastfeeding)-392.1(and)-388.9(radiologic)-388.6(procedures.)]TJ
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(Can)Tj
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[(Fam)-333.3(Physician)]TJ
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[(7.)-500.4(Obenauer)-328.7(S,)-320.3(Dammert)-329.1(S.)-326.4(Palpable)-326.6(masses)-329.5(in)-329.1(breast)-327.3(during)]TJ
1.2503 -1.1223 TD
(lactation.)Tj
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[(Clin)-333.6(Imaging)]TJ
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[(8.)-500.4(Robbins)-455.7(J,)-456.8(Jeffries)-465.5(D,)-459.2(Roubidoux)-456.9(M,)-456.9(et)-461.4(al.)-455.3(Accuracy)-467.1(of)]TJ
1.2503 -1.1223 TD
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[(nancy)-250.1(a)-4.2(nd)-250.1(lact)-5.6(ation)-6.1(.)]TJ
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[(AJ)3.1(R)-256.9(A)5.4(m)-256.6(J)-253.1(R)5.4(o)1.2(entgenol)]TJ
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[(2011)-6.2(;196:716722.)]TJ
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[(9.)-500.4(Sabate)-363.5(JM,)-358.6(Clotet)-361.9(M,)-365.4(Torrubia)-359(S,)-363(et)-363.8(al.)-357.7(Radiologic)-366.7(evalu-)]TJ
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[(ation)-272.2(of)-277.1(breast)-278.5(disorders)-282.3(related)-277.1(to)-274.2(pregnancy)-278.5(and)-279.1(lactation.)]TJ
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(Radiographics)Tj
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[(2007;27)-335.9(Suppl)-332.4(1:S101S124.)]TJ
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[(10.)-500.5(Talele)-386.3(AC,)-384.9(Slanetz)-381.3(PJ,)-386.6(Edmister)-385.3(WB,)-381.5(et)-382.1(al.)-388.2(The)-384.7(lactating)]TJ
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[(breast:)-253.7(MRI)-250.8(ndings)-252.5(and)-248.6(literature)-254.3(review.)]TJ
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17.3462 0 TD
[(Breast)-254.7(J)]TJ
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(237240.)Tj
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[(mon)-244.2(b)5.9(enign)-244.2(e)1.7(ntities.)]TJ
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[(AJR)-246.1(A)-2.1(m)-245.8(J)-242.3(Roentgenol)]TJ
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[(2013)6.1(;)-5.6(2)6.1(00:32933)6.1(6.)]TJ
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[(12.)-500.5(American)-303.3(College)-305.8(of)-307.6(Radiology.)-302(ACR)-304.3(Manual)-306.8(on)-305.2(Contrast)]TJ
1.7505 -1.1223 TD
[(Media.)-245.8(Administration)-243.8(of)-246.6(contrast)-241.6(media)-246(to)-243.7(women)-243.9(who)-246(are)]TJ
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[(breast-feeding.)-383.7(2018)-372.6(\(Version)-382.2(10.3\),)-381.2(99100.)-373(Available)-385.8(at)]TJ
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[(13.)-500.5(Davis)-364.9(PL.)-365(Anaphylactoid)-374.2(reactions)-368(to)-365.7(the)-363.9(nonvascular)-368.8(ad-)]TJ
1.7505 -1.1223 TD
[(ministration)-254.2(of)-258.8(water-soluble)-256(iodinated)-258.1(contrast)-259.9(media.)]TJ
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(AJR)Tj
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[(14.)-500.5(Bettmann)-750.8(MA.)-745.3(Frequently)-751.9(asked)-746.3(questions:)-752.4(Iodinated)]TJ
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(Radiographics)Tj
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[(2004;24)-335.9(Suppl)-332.4(1:S3S10.)]TJ
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[(15.)-500.5(Webb)-295.8(JA,)-293.8(Thomsen)-298.6(HS,)-297.6(Morcos)-292.4(SK;)-297.1(Members)-302.5(of)-295.4(Contrast)]TJ
1.7505 -1.1284 TD
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[(Eu)16.1(r)-377.4(R)0(a)22.2(d)0(i)18.6(o)0(l)]TJ
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